Harnessing Population-Scale Biodata: Leveraging Data from the All of Us Researcher Workbench and BCM's IMAGINE Program for Precision Health
June 25, 2025
Biodata Stage
- Population genetic screening involves systematically analyzing genetic variants across large groups to identify individuals at elevated risk for inherited conditions, thereby improving early detection, prevention, and personalized management of diseases.
- The All of Us Research Program is an NIH-led initiative gathering health data from one million diverse participants to advance precision medicine, providing researchers with controlled access to comprehensive genomic, clinical, and lifestyle datasets via its Researcher Workbench.
- Baylor College of Medicine's IMAGINE Research Program seeks to enroll over 120,000 patients to enhance understanding of genetic influences on health and disease through research, aiming to lead to personalized care recommendations.
- Data from these programs has diverse applications, including studying disparities in known pathogenic variation, G6PD deficiency in the context of severe COVID-19 and risk variants for chronic liver disease.
