Phenomic Foundation Models for Drug Discovery
June 25, 2025
AI in Drug Discovery Stage
- Large-Scale Cell Microscopy for Drug Discovery: High-throughput imaging screens for analyzing chemical/genetic perturbations.
- Scaling Foundation Models for Microscopy Data: Largest vision transformer model trained on 8B image crops, achieving 60% improvement in phenotypic feature separability.
- Key Innovations in Model Training: Curated dataset, biologically motivated probing, and leveraging intermediate blocks for better representations.
- Breakthroughs in Drug Discovery Applications: Improved known relationship recall, enhanced screening reliability, and scalable AI-driven biological modeling.
- Future Directions: Expansion to other biomedical domains, multi-modal data integration, and advancing AI-powered drug discovery.
