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Agenda

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Agenda

Below are the keynote sessions for each day, followed by the 7 theatres of presentations and panel discussions. 

For a quick top-down overview of the topics being covered at the Festival, we recommend looking at the Agenda at a Glance here. It's the best way to quickly make sense of the theatres, individual sessions and roundtable discussions.

To see the Detailed Agenda for each of the seven theatres, including workshops and roundtable discussions, click here.

 

KEYNOTE SESSIONS

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Innovation Stage
  1. Innovation Stage
    Reflection on the advances in the field of genomics since The Human Genome Project   Genomic medicin ...
  2. Innovation Stage
  3. Innovation Stage
    TBC
  4. Innovation Stage
    In this fireside chat, we will discuss what the last two decades of genomics has brought to the fore ...
Innovation Stage
  1. Innovation Stage
  2. Innovation Stage
    In this talk, Carl Zimmer will give us an overview of the odyssey through the living atmosphere and ...
  3. Innovation Stage
    TBC
  4. Innovation Stage
    TBC
  5. Innovation Stage
    The Longitude Prize series brings together the brightest minds to solve the world's most challenging ...
  6. Innovation Stage
    Sponsored by Castle Biosciences 
  7. Innovation Stage
    Can groundbreaking innovations in AI, multi-omics, and biodata reduce the traditional $2.5 billion, ...

 

THEATRE SESSIONS

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Innovation Stage
  1. Innovation Stage
    The latest breakthroughs in genomic sequencing, highlighting their impact on healthcare, research, a ...
  2. Innovation Stage
  3. Innovation Stage
    Long read sequencing holds great promise in the direct detection of DNA modifications It's important ...
  4. Innovation Stage
  5. Innovation Stage
  6. Innovation Stage
    Understand the importance of pre-analytical sample preservation Explore the potential of cell-free D ...
  7. Innovation Stage
  8. Innovation Stage
  9. Innovation Stage
    Optimization of long-read sequencing for single-cell transcriptomics. Elucidation of transcript dive ...
  10. Innovation Stage
    Sponsored by Oxford Nanopore
  11. Innovation Stage
    1. Discuss the role of molecular characterization in brain tumors.  2) discuss several clinical exam ...
  12. Innovation Stage
  13. Innovation Stage
    Applying long read sequencing to population-scale studies to identify new structural variants associ ...
  14. Innovation Stage
    TBC
  15. Innovation Stage
    Integrating Data to Uncover Molecular Mechanisms of Cancer Development and Genotype-Phenotype Insigh ...
AI in Drug Discovery Stage
  1. AI in Drug Discovery Stage
    Explore how machine learning algorithms and AI-driven data analysis are transforming the early stage ...
  2. AI in Drug Discovery Stage
    TBC
  3. AI in Drug Discovery Stage
    Overview of Target Identification and Validation in drug discovery and research Importance of FAIR ( ...
  4. AI in Drug Discovery Stage
  5. AI in Drug Discovery Stage
    Explore how foundation models are used to generate new molecular structures and predict their proper ...
  6. AI in Drug Discovery Stage
    TBC
  7. AI in Drug Discovery Stage
    Leveraging A Single Cell Foundation Model to Identify Primary Resistance Signals  Utilizing single-c ...
  8. AI in Drug Discovery Stage
  9. AI in Drug Discovery Stage
    Investigate how AI/ML models assess the activity and safety of small molecules in early drug discove ...
  10. AI in Drug Discovery Stage
    TBC
  11. AI in Drug Discovery Stage
    How are you using machine learning models for target discovery and validating AI-identified targets? ...
Biodata Stage
  1. Biodata Stage
    Scaling Big Genomics Data to Support Drug Development Strategy Modernising Genomic Data Management S ...
  2. Biodata Stage
      Scientific data (Multi-Omics, Spatial) is growing exponentially in size and complexity Biotechs ne ...
  3. Biodata Stage
    Healthcare system-linked biobanks such as the VA Million Veteran Program have the opportunity to tra ...
  4. Biodata Stage
  5. Biodata Stage
    This talk will demonstrate how to integrate large-scale tumor-derived and clinical genomic data sets ...
  6. Biodata Stage
  7. Biodata Stage
    We'll discuss the importance of making multi-modal, real world cancer patient data available and int ...
  8. Biodata Stage
  9. Biodata Stage
    The GDC houses multi-omic and clinical data for > 44K cases, spanning 36 types of cancer across 86 p ...
  10. Biodata Stage
    TBC
  11. Biodata Stage
    In this presentation, we explore the genomic frontiers of Alzheimer’s research through the groundbre ...
Cancer Diagnostics Stage
  1. Cancer Diagnostics Stage
    Uncover how integrating epigenomic data with genomic, transcriptomic, and proteomic data provides a ...
  2. Cancer Diagnostics Stage
  3. Cancer Diagnostics Stage
    Breast cancer now undergoes routine molecular phenotyping leading to improved prognostication and us ...
  4. Cancer Diagnostics Stage
  5. Cancer Diagnostics Stage
    This talk will demonstrate how methylation biomarkers can be detected from liquid biopsy tests to su ...
  6. Cancer Diagnostics Stage
    TBC
  7. Cancer Diagnostics Stage
    Liquid biopsies could improve cancer detection and monitoring but require higher sensitivity First, ...
  8. Cancer Diagnostics Stage
  9. Cancer Diagnostics Stage
    Using a multi-modal approach to liquid biopsy combining genomics, epigenomics and fragmentomic assay ...
  10. Cancer Diagnostics Stage
    TBC
  11. Cancer Diagnostics Stage
    Incorporation of MRD in the CDP life cycle and beyond for solid and hematologic cancers You will lea ...
Multi-Omics Stage
  1. Multi-Omics Stage
    Integrating multi-Omics data to model gene regulatory networks can provide unprecedented insights in ...
  2. Multi-Omics Stage
  3. Multi-Omics Stage
    Explore how HIP integrates high-dimensional multi-view omic data to improve prediction accuracy and ...
  4. Multi-Omics Stage
  5. Multi-Omics Stage
    Analysis of multi-omics data is challenging and rewarding as every omics modality reveals unique ins ...
  6. Multi-Omics Stage
    TBC
  7. Multi-Omics Stage
    Explore how integrating multi-omics data with knowledge graphs enhances target discovery by revealin ...
  8. Multi-Omics Stage
  9. Multi-Omics Stage
    Greater degree of success from human-genetics anchored target & drug discovery.  Translationally-rel ...
  10. Multi-Omics Stage
    TBC
  11. Multi-Omics Stage
    Spatial profiling technologies enable multi-modal characterization of the tissue microenvironment, r ...
Proteomics Stage
  1. Proteomics Stage
    Progress and current pitfalls of high-throughput proteomics How can proteomics fill many of the void ...
  2. Proteomics Stage
    Introduction to Next-Gen Protein Sequencing™ (NGPS™) on Platinum® Pro—a cutting-edge single-molecule ...
  3. Proteomics Stage
    Mass spectrometry-based proteomics methods are rapidly advancing with improved sensitivity, throughp ...
  4. Proteomics Stage
  5. Proteomics Stage
    This talk will cover the development of a proteomics-based aging clock using plasma protein data fro ...
  6. Proteomics Stage
    Proteogenomic quantification to create patient-specific tumor “atlas” Targetable dependencies of dru ...
  7. Proteomics Stage
  8. Proteomics Stage
    Studying the proteogenomic landscape of TNBC appears to be a promising method to identify therapeuti ...
  9. Proteomics Stage
    TBC
  10. Proteomics Stage
      Recent advances in proteomic technologies, coupled with next generation sequencing, has enabled pr ...
Single-Cell and Spatial
  1. Single-Cell and Spatial
    Single cell atlases as a cellular road map Cross-disease analysis of single cell atlases reveals pat ...
  2. Single-Cell and Spatial
  3. Single-Cell and Spatial
    Single cell and spatial transcriptomics data are new types of data that offer in-depth knowledge on ...
  4. Single-Cell and Spatial
  5. Single-Cell and Spatial
    Single-Cell Sequencing to Evaluate ABBV-CLS-484: A first in class, first in mechanism PTPN1/2 inhibi ...
  6. Single-Cell and Spatial
    Sponsored by Scale Biosciences 
  7. Single-Cell and Spatial
    Single cell profiling was used to perform multi-parametric screening of vaccine candidates Vaccine d ...
  8. Single-Cell and Spatial
    An efficient and cost-effective strategy for routinely profiling millions of single-cell transcripto ...
  9. Single-Cell and Spatial
        • Description of the Flexomics solution for collecting paired phenotypic/functional and transcri ...
  10. Single-Cell and Spatial
    Cancer arises from the interplay of genetic and non-genetic factors, including cell identity, epigen ...
Genome Dome
  1. Genome Dome
    Roundtable Discussion: Building Inclusivity and Trust in Genomics Genomics has the power to transfor ...
  2. Genome Dome
  3. Genome Dome
    AI is transcending the realm of buzzwords to become a crucial component in modern medicine. It has t ...
  4. Genome Dome
  5. Genome Dome
    How are AI and digital pathology shaping the way we diagnose and treat diseases? With the increasing ...
AI in Drug Discovery Stage
  1. AI in Drug Discovery Stage
    Understand how genomics and iPSCs are used to model diseases, identify genetic mutations, and study ...
  2. AI in Drug Discovery Stage
    TBC
  3. AI in Drug Discovery Stage
    Large-Scale Cell Microscopy for Drug Discovery: High-throughput imaging screens for analyzing chemic ...
  4. AI in Drug Discovery Stage
  5. AI in Drug Discovery Stage
    Case studies on two mature sequence learning applications for target finding and drug discovery at G ...
  6. AI in Drug Discovery Stage
    Connected Digital Ecosystem: Creating an end-to-end digital infrastructure that seamlessly integrate ...
  7. AI in Drug Discovery Stage
    How can the integration of diverse data sources, such as genomic, clinical, and real-world data, enh ...
Biodata Stage
  1. Biodata Stage
    TakOmics is a FAIR multi-omics data management and analytics platform designed to address complex om ...
  2. Biodata Stage
    In this talk, titled "Unlocking the Secrets of Data: Challenges and Solutions in the Discovery Value ...
  3. Biodata Stage
    Getting Started with Quantum Computing: Practical steps for integrating quantum computing into an en ...
  4. Biodata Stage
  5. Biodata Stage
    Large scale multi-omics can empower drug discovery and development at every pipeline stage We talk, ...
  6. Biodata Stage
    Demonstrate how population-scale proteogenomic studies can support the identification of new biomark ...
  7. Biodata Stage
    Population genetic screening involves systematically analyzing genetic variants across large groups ...
Cancer Diagnostics Stage
  1. Cancer Diagnostics Stage
    Establishing liquid biopsies for early cancer detection and screening. Where can they most provide v ...
  2. Cancer Diagnostics Stage
    TBC
  3. Cancer Diagnostics Stage
    Negative selection-based microfluidic technologies enable high resolution multi-omic profiling of ra ...
  4. Cancer Diagnostics Stage
  5. Cancer Diagnostics Stage
    Mass-spectrometry-based proteomic analysis on extracellular vesicles to uncover new biomarkers to su ...
  6. Cancer Diagnostics Stage
    The emerging promise of T cell receptor therapies (TCR-Ts) for cancer treatment Navigating challenge ...
  7. Cancer Diagnostics Stage
    Jemperli (dostarlimab), an immunotherapy received FDA's "Breakthrough Therapy Designation" for treat ...
Multi-Omics Stage
  1. Multi-Omics Stage
    Values: Offer detailed insights into proteome-level changes and integrate with genomic data to suppo ...
  2. Multi-Omics Stage
    TBC
  3. Multi-Omics Stage
    You will hear how expanding and diversifying genomic datasets and creating novel analytical methods ...
  4. Multi-Omics Stage
  5. Multi-Omics Stage
    investigate how integrating genomic, transcriptomic, and imaging data helps identify key molecular f ...
  6. Multi-Omics Stage
    Explore the integration of diverse imaging modalities to enhance radiomic feature extraction and imp ...
  7. Multi-Omics Stage
    Experimental validation of predicted key-regulators Single-cell network inference Multi-omics bulk a ...
Proteomics Stage
  1. Proteomics Stage
    Using high-throughput proteomic profiling to identify new exploratory biomarkers from blood samples. ...
  2. Proteomics Stage
    TBC
  3. Proteomics Stage
    Common animal models for atherosclerosis entail genetic manipulation of lipid metabolizing proteins. ...
  4. Proteomics Stage
  5. Proteomics Stage
    Building a computational workflow to probe and analyze multiomic datasets Spatial analysis methodolo ...
  6. Proteomics Stage

    Organ systems are composed of unique cell types that actively coordinate to enable higher order functions. Even slight deviances in the molecular or cellular states of these systems can result in debilitating disorders whose severity, treatment course, and overall treatment outcome vary widely from patient to patient.

    This level of complexity likely contributes to promising therapeutics failing within clinical trials and, thus, require further exploration. Thus, the Neumann lab focuses on developing and applying multimodal imaging and profiling techniques to study the molecular and cellular architecture behind complex human diseases, such as renal cell carcinoma, Alzheimer’s Disease, and Canavan’s Disease.

    To do this, we combine multiple analytical tools to detect molecules throughout the central dogma of biology, including genes, proteins, and metabolites.

    Our main instrument is the Bruker timsTOF fleX MALDI MS system, which enables us to detect hundreds to thousands of metabolomic features at <10 µm spatial resolution.

    In conjunction with immunohistochemistry and spatial transcriptomics, we can connect these metabolomic profiles to specific cell types and cell states. These integrated technologies can be used on a variety of biological samples with high reproducibility and rigor. 

  7. Proteomics Stage
    Integrated analysis of high-resolution, high-plex spatial transcriptomics and proteomics allows for ...
Single-Cell and Spatial
  1. Single-Cell and Spatial
    A hierarchical Bayesian model jointly models and aligns spatial transcriptomic, spatial proteomic, a ...
  2. Single-Cell and Spatial
    Spatial biology unlocks new insights into tissue and cell biology.  Our AI-powered analysis allows i ...
  3. Single-Cell and Spatial
    How does spatial molecular pathology provide insights into tissue architecture and patient heterogen ...
  4. Single-Cell and Spatial
  5. Single-Cell and Spatial
    Problem: Too many potential explanations/hypotheses for disease progression and treatment response t ...
  6. Single-Cell and Spatial
    Explore how single-cell transcriptomic analysis reveals gene expression patterns in individual cells ...
  7. Single-Cell and Spatial

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