While the genome is static, the epigenome is dynamic; shaped by environment and behavior, influencing disease onset and progression.

This track will cover new advances in epigenetic biomarkers, diagnostics and therapies, and explore how epigenetics is driving novel approaches in research and clinical innovation. 

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11:30
  1. Unraveling Histone Modification Machinery: Structural Mechanisms of Epigenetic Regulation in Cancer
    Epigenetics Stage
    30 mins
    Revealing the structural mechanisms of histone-modifying complexes  Understanding how epigenetic machinery controls gene regulation  Insights into chromatin regulation and implications for cancer biol …
    Speakers
    Speaker image for Evan Worden
    Evan Worden, Asistant Professor - Van Andel Institute
12:00
  1. Sponsored Slot Available
    Epigenetics Stage
    30 mins
12:30
  1. Stem Cell States in Neural Regeneration
    Epigenetics Stage
    30 mins
    Olfactory epithelial stem cells give rise to multiple cell types during development and after injury  Single cell profiling reveals multiple epigenetic states of olfactory stem cells during homeostasi …
    Speakers
    Speaker image for Whitney Heavner
    Whitney Heavner, Scientist - National Institute of Neurological Disorders and Stroke (NINDS)
14:10
  1. Taming The Unknown: Pragmatic Epigenetic Approaches in Cancer Risk Assessment and Treatment
    Epigenetics Stage
    30 mins
    Cancer is a genetic and epigenetic disease. Epigenetic modifications, especially DNA methylation, selected histone modifications, miRNAs, and non-coding RNAs play a role in carcinogenesis and have bee …
    Speakers
    Speaker image for Mukesh Verma
    Mukesh Verma, Chief, Cancer Epidemiology - Genomics Research Program, NCI (NIH)
14:40
  1. Sponsored Slot Available
    Epigenetics Stage
    30 mins
15:10
  1. Epigenetic Signatures Linking Alzheimer’s Genetic Risk and Alcohol Use Disorder
    Epigenetics Stage
    30 mins
    We present shared and distinct genetic and epigenetic mechanisms across five substance use disorders that shape patterns of comorbidity.   Building on this broader framework and given the known links …
    Speakers
    Speaker image for Gita Pathak
    Gita Pathak, Assistant Professor - Icahn School of Medicine at Mount Sinai
16:10
  1. DropC Allows Scalable and Multimodal Profiling of Genetic and Non-Genetic Determinants of Human Leukemia
    Epigenetics Stage
    30 mins
    Deciphering cancer progression and therapeutic response requires studying both genetic and non-genetic determinants of tumour heterogeneity. To address this, we developed DropC, a high-throughput sing …
    Speakers
    Speaker image for Giovanni Gambi
    Giovanni Gambi, Postdoctoral Researcher - NYU Langone Health
16:40
  1. Sponsored Slot Available
    Epigenetics Stage
    30 mins
17:10
  1. AI for Single-Cell Regulatory Genomics
    Epigenetics Stage
    30 mins
    Speakers
    Speaker image for Christina Leslie
    Christina Leslie, Principal Investigator - Memorial Sloan Kettering Cancer Center
11:30
  1. DNA Topology, Chromatin Structure and Therapeutic Control
    Epigenetics Stage
    30 mins
    Speakers
    Speaker image for Taekjip Ha
    Taekjip Ha, Professor - Harvard Medical School and Boston Children’s Hospital
12:00
  1. More details to be announced shortly
    Epigenetics Stage
    30 mins
    Speakers
    Speaker image for Yasser Riazalhosseini
    Yasser Riazalhosseini, Associate Professor, Department of Human Genetics - McGill University
12:30
  1. Inherited Metabolism: How Early-Life Stress Reprograms the Epigenome Across Generations
    Epigenetics Stage
    30 mins
    How parental and early-life metabolic stress reshapes the epigenome during critical developmental windows  Mechanisms of epigenetic inheritance linking early metabolic environments to obesity risk in …
    Speakers
    Speaker image for Nabil Rabhi
    Nabil Rabhi, Research Assistant Professor - Boston University
14:00
  1. Single-cell 3D Genome Organization in Leukemia with DROP-C
    Epigenetics Stage
    30 mins
    DROP-C, a novel single-cell multi-modal assay for 3D genome organization  A novel deep learning framework for Hi-C data resolution augmentation  Single-cell 3D-omics in leukemia 
    Speakers
    Speaker image for Guido Barzaghi
    Guido Barzaghi, Postdoctoral Fellow in the Tsirigos Lab - NYU Grossman School of Medicine
14:30
  1. Structure and Function of ATP-Dependent Chromatin Remodeling Complexes in Health and Disease
    Epigenetics Stage
    30 mins
    Structural and mechanistic insights into how ATP-dependent chromatin remodeling complexes (including SWI/SNF/BAF) regulate genome accessibility and transcriptional control  The role of chromatin remod …
    Speakers
    Speaker image for Cigall Kadoch
    Cigall Kadoch, Professor - Dana-Farber Cancer Institute
15:00
  1. How Enhancer Mutations Drive Ovarian Cancer Through RNA-Mediated Epigenetic Regulation
    Epigenetics Stage
    30 mins
    The noncoding genome problem — most cancer-associated variants lie outside genes, limiting interpretation and clinical translation.  Enhancer RNAs as active epigenetic regulators — eRNAs control mRNA …
    Speakers
    Speaker image for Natalia Benova
    Natalia Benova, PhD Candidate - Leeds Beckett University