Day 1 explores how the latest innovations in next-generation sequencing are transforming speed, scale, accuracy and cost, and how new sequencing approaches unlock everything from population-scale studies to routine clinical use.

Day 2 focuses on advanced genome analysis, including peta-byte scale infrastructure and AI-driven variant interpretation. 

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09:00
  1. AI for Genomic Medicine: A Multimodal Deep Learning Journey from Molecules to Single Cells
    Innovation Stage
    30 mins
    Empowering genomic medicine by unifying chemical, protein, and single-cell data through multimodal AI  Elevating biological insight across scales, from molecular structure to cellular function  Transf …
    Speakers
    Speaker image for Manolis Kellis
    Manolis Kellis, Professor of Computer Science - MIT
09:30
  1. More details to be announced shortly
    Innovation Stage
    30 mins
    Sponsored by N6
10:00
  1. Panel Discussion: From Hype to Translational Value: AI & Machine Learning Powering Precision Drug Discovery
    Innovation Stage
    30 mins
    Translate AI/ML innovation into a scalable impact across the drug discovery pipeline, from portfolio strategy to pipeline velocity  Differentiate sustainable competitive advantage from short-term hype …
    Speakers
    Speaker image for Justin Scheer
    Justin Scheer, VP, In Silico Discovery - Johnson & Johnson Innovative Medicines
    Speaker image for John Chan
    John Chan, Global Head of Digital, Informatics and AI - Novartis
    Speaker image for Aziz Nazha
    Aziz Nazha, Global Head, AI Innovations - Incyte
    Speaker image for Justin H. Johnson
    Justin H. Johnson, Executive Director, Oncology Data Science - AstraZeneca Oncology R&D
10:30
  1. The AI-Driven Future of Health: From Genomes to Wearables and Predictive Wellness
    Innovation Stage
    30 mins
    Data-driven health with lead to a healthcare for each individual focused on wellness and prevention that will replace our current focus on disease care.  The genome provides the source code for the po …
    Speakers
    Speaker image for Leroy Hood
    Leroy Hood, CEO & President - Phenome Health & Institute for Systems Biology (ISB)
11:00
  1. Networking Break
    Innovation Stage
    30 mins
11:30
  1. From Genomics to the Next Frontier: 20 Years of Innovation and What Comes Next
    Innovation Stage
    30 mins
    Reflecting on two decades of progress in genomics and why the field is now at a pivotal inflection point  The shift toward multiomics, single-cell and spatial technologies, and the integration of AI-d …
    Speakers
    Speaker image for Niall Lennon
    Niall Lennon, Senior Director, Genomics Platform - The Broad Institute of MIT and Harvard
12:00
  1. Sponsored Slot Available
    Innovation Stage
    30 mins
12:30
  1. One Run, Every Variant: Simplifying Complex Diagnostics through Long-Read Sequencing
    Innovation Stage
    30 mins
    Discuss the evolution of sequencing technologies and describe opportunities and challenges for implementing long-read sequencing into clinical diagnostics.  Describe a comprehensive clinical workflow …
    Speakers
    Speaker image for Bharat Thyagarajan
    Bharat Thyagarajan, Laboratory Medicine and Pathology Vice Chair for Translational Research - University of Minnesota
13:05
  1. More details to be announced shortly
    Innovation Stage
    15 mins
    Sponsored by Single Cell Discoveries
13:20
  1. More details to be announced shortly
    Innovation Stage
    15 mins
    Sponsored by Omega Bio-tek
13:35
  1. Sponsored Slot Available
    Innovation Stage
    15 mins
13:50
  1. Sponsored Slot Available
    Innovation Stage
    15 mins
14:10
  1. Nanopore-Based Random Genomic Sampling to Diagnose Neurodegenerative Disease at an Ultra-Fast Speed
    Innovation Stage
    30 mins
    Development of intra-operative molecular diagnosis based on copy number variation and methylation classification. Implementation of an online platform for data analysis. Expansion of the technology to …
    Speakers
    Speaker image for Chun-Chieh Lin
    Chun-Chieh Lin, Assistant Professor of Pathology, Geisel School of Medicine - Dartmouth College
14:40
  1. Sponsored Slot Available
    Innovation Stage
    30 mins
15:10
  1. Discovery of Novel Targets – Application of Genomic Sequencing Technologies
    Innovation Stage
    30 mins
    Application of genomic sequencing technologies is transforming drug target discovery and therapeutics development  Oxford Nanopore long read sequencing enables identification of patient-specific, dise …
    Speakers
    Speaker image for Yuxin Liang
    Yuxin Liang, Senior Principal Scientific Manager - Genentech
16:10
  1. Exomes, Genomes, Multi-Omics: Navigating the Space Between Today’s Standards and Tomorrow’s Diagnostics
    Innovation Stage
    30 mins
    Discuss scope and limitations of shot-read sequencing and highlight case examples where re-analysis with sophisticated tools may reveal novel diagnoses. Discuss scope and limitations of current use of …
    Speakers
    Speaker image for Ramakrishnan Rajagopalan
    Ramakrishnan Rajagopalan, Director of Translational Bioinformatics - Children's Hospital of Philadelphia
16:40
  1. Towards Pre-Symptomatic Diagnosis of Alzheimer’s Disease: Unlocking Isoform-Level Biomarkers
    Innovation Stage
    30 mins
    Moving beyond gene-level expression to identify targetable RNA isoforms linked to early Alzheimer’s disease  Large-scale analysis of frontal cortex transcriptomes reveals isoform signatures that disti …
    Speakers
    Speaker image for Mark Ebbert
    Mark Ebbert, Associate Professor - University of Kentucky
17:10
  1. Panel Discussion: How Do The Sequencing Technology Advancements Drive Translational Research?
    Innovation Stage
    30 mins
    Which recent sequencing advances have most changed how we move discoveries from basic research toward practical applications?  How has improved resolution and scale in sequencing (like single-cell or …
    Speakers
    Speaker image for Miten Jain
    Miten Jain, Assistant Professor of Bioengineering and Physics - Northeastern University
    Speaker image for Bharat Thyagarajan
    Bharat Thyagarajan, Laboratory Medicine and Pathology Vice Chair for Translational Research - University of Minnesota
    Speaker image for Jing Colatat
    Jing Colatat, Senior Scientist, Vaccine R&D - Pfizer
09:15
  1. Rewriting the Human Genome: From Fragmented References to True Diploid Genomics
    Innovation Stage
    30 mins
    Speakers
    Speaker image for J. Craig Venter
    J. Craig Venter, Founder, Chairman, and CEO - J. Craig Venter Institute
09:45
  1. Reserved for Pure Storage
    Innovation Stage
    30 mins
10:15
  1. Panel Discussion: Multi-Modal Data at Scale: Discovery, Governance, and Trust
    Innovation Stage
    45 mins
    Operationalizing multi-modal data (omics, imaging, clinical, real-world) at scale to accelerate discovery and enable precision medicine.  Establishing robust governance frameworks to ensure data quali …
    Speakers
    Speaker image for John Tallarico
    John Tallarico, Global Head of Discovery Sciences - Novartis
    Speaker image for Stacey Gabriel
    Stacey Gabriel, Executive Vice President, Platforms and Scientific Execution - The Broad Institute of MIT and Harvard
    Speaker image for Melina Claussnitzer
    Melina Claussnitzer, Director, Broad Diabetes Initiative - Broad Institute
    Speaker image for Woody Sherman
    Woody Sherman, Founder and Chief Innovation Officer - PsiThera
10:30
  1. More details to be announced shortly
    Innovation Stage
    30 mins
11:00
  1. Networking Break
    Innovation Stage
    30 mins
11:30
  1. Right Read for the Right Task: Orchestrating Multiple NGS Platforms Across the Biologics Pipeline
    Innovation Stage
    30 mins
    NGS platforms are suitable for different tasks depending on their read length, accuracy and throughput.   Orchestration of multiple NGS platforms on Biologics development balances speed, cost and perf …
    Speakers
    Speaker image for Yang Song
    Yang Song, Associate Principal Scientist - AstraZeneca
12:00
  1. Sponsored Slot Available
    Innovation Stage
    30 mins
12:30
  1. Big Data, Big Problems: Building Infrastructure for Research at Any Scale
    Innovation Stage
    30 mins
    Big data problems affect teams of all sizes: From large international consortia like ICGC-ARGO coordinating 100,000+ patient genomes, to individuals in small labs generating terabytes of sequencing da …
    Speakers
    Speaker image for Mitchell Shiell
    Mitchell Shiell, Product Manager - Ontario Institute for Cancer Research
14:00
  1. Decoding the Language of Life: A Large Language Model for the RNA World
    Innovation Stage
    30 mins
    Building the first language model for non-coding RNA and regulatory RNA logic  RNA facial recognition: compressing transcriptomes into images that reveal cell state 
    Speakers
    Speaker image for John Rinn
    John Rinn, Professor - Boulder Department University of Colorado
14:30
  1. tRNA Isodecoder Analysis using Nanopore Ionic Current Signals and Deep Learning
    Innovation Stage
    30 mins
    Speakers
    Speaker image for Miten Jain
    Miten Jain, Assistant Professor of Bioengineering and Physics - Northeastern University
15:00
  1. Using Machine Learning to Predict Compound Polypharmacology
    Innovation Stage
    30 mins
    Chemogenomics data was integrated from multiple sources.    Machine learning models were built to predict the polypharmacology (multi-target) profile of a given chemical structure 
    Speakers
    Speaker image for Stephen Capuzzi
    Stephen Capuzzi, Principal Scientist, Data and Computational Sciences - Vertex Pharmaceuticals