Advances in Single-cell and Long-read Sequencing Converge for Novel Insights in Alzheimer’s Disease

June 04, 2026
Multi-Omics Integration Stage
  • Genetic variants impact Alzheimer’s Disease risk 

  • Molecular consequences of Alzheimer’s disease pathology are cell type-specific 

  • Altered splicing is implicated in AD susceptibility 

  • Single-cell multiomics plus long-read sequencing allows comprehensive cell-type level assessment of splicing dysregulation

Speakers
Lindsay Rizzardi
Lindsay Rizzardi, Assistant Professor, Department of Biochemistry and Molecular Genetics - The University of Alabama at Birmingham