Discovery of Novel Targets – Application of Genomic Sequencing Technologies
- Application of genomic sequencing technologies is transforming drug target discovery and therapeutics development
- Oxford Nanopore long read sequencing enables identification of patient-specific, disease relevant microbial species, facilitating understanding of disease pathobiology and development of therapeutic strategies for IBD
- Ribo-seq enables discovery of HLA-I peptide and proteins derived from novel unannotated open reading frames, facilitating novel antigen discovery for cancer immunotherapy and novel protein discovery for therapeutic targets