Speakers

Bruno Matuck is DDS, PhD and serves as Principal Investigator of the Oral Systems Biology Lab (LaBBioS) at Hospital Israelita Albert Einstein in São Paulo, Brazil. His research integrates spatial transcriptomics, spatial proteomics, and digital pathology to study immune–stromal interactions in human tissues. A central component of his work is the systematic analysis of human autopsy specimens, enabling whole-body, multi-organ investigation of disease processes within preserved tissue architecture. His main research focus includes allo-immune diseases such as chronic graft-versus-host disease, aging-associated tissue remodeling, and head and neck squamous cell carcinoma.

He is particularly interested in fibroblast heterogeneity across oral and mucosal tissues and in the aging of exocrine glands, investigating how structural cells shape immune organization and tissue degeneration. By combining high-resolution spatial technologies with computational analysis, his group aims to define multicellular modules that drive chronic inflammation, fibrosis, and organ dysfunction across diseases.