The Innovation Stage will host the morning keynote presentations. It will also explore cutting-edge sequencing technologies, epigenetics, and how to leverage the latest technologies for deep molecular profiling.
09:00
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Innovation Stage30 minsReflection on the advances in the field of genomics since The Human Genome Project Genomic medicine implementation and the vital role that genomic information can play in clinical care Navigating t ...Speaker(s)
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09:30
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Innovation Stage30 minsHow is the Genomics Ecosystem Responding to the Current Climate The US life sciences sector stands at a critical crossroads, facing both unprecedented challenges in funding and opportunities for innov ...
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10:00
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Innovation Stage30 minsIn this session we will explore the journey from bench to bedside, the needs to pass through a complex, heavily regulated environment both for diagnostics and discovery. Also being covered: The jour ...
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10:30
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Innovation Stage30 minsIn this fireside chat, we will discuss what the last two decades of genomics has brought to the forefront of human medicine – from longevity, synthetic life, microbial genomics and more.
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11:00
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Innovation Stage30 mins
11:30
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Innovation Stage30 minsThe latest breakthroughs in genomic sequencing, highlighting their impact on healthcare, research, and personalised medicine. Innovations in next-generation sequencing (NGS), long-read sequencing tech ...
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12:00
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Innovation Stage30 minsThis presentation will provide insight into Roche’s breakthrough next-generation sequencing technology, Sequencing By Expansion (SBX). SBX is a novel sequencing approach that uses an elegant biochemic ...
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12:30
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Innovation Stage30 minsLong read sequencing holds great promise in the direct detection of DNA modifications It's important to recognize a few challenges, especially false positive detections How to navigate the pitfalls in ...Speaker(s)
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13:05
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Innovation Stage15 minsAutomated high-throughput experiments with Biomek i-Series Workstations and Echo Acoustic Liquid Handlers significantly reduces manual processing time and increases sample throughput, enabling faster ...
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13:20
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Innovation Stage15 minsAs single-cell research matures, adding spatial context is the next frontier, revealing what cells are doing and where they are acting within complex tissue environments. This talk highlights how spat ...
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13:35
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Innovation Stage15 minsUnderstand the importance of pre-analytical sample preservation Explore the potential of cell-free DNA (cfDNA) as a non-invasive analyte Interpret and Analyze ddPCR Data
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13:50
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Innovation Stage15 minsIn this talk, we will discuss Trekker™ technology—a new class of spatial technology designed to acquire spatial and single-cell data in a single experiment. Current spatial technologies sacrifice sens ...
14:10
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Innovation Stage30 minsOptimization of long-read sequencing for single-cell transcriptomics. Elucidation of transcript diversity (e.g. splicing, allelic imbalance, alternative UTRs). Applications in cancer biology and neuro ...
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14:40
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Innovation Stage30 minsShort cell-free DNA fragments can be sequenced at scale with Oxford Nanopore sequencing Direct single molecule measurement of cfDNA methylation enables a promising biomarker modality for cancer detect ...
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15:10
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Innovation Stage30 mins1. Discuss the role of molecular characterization in brain tumors. 2) discuss several clinical examples that can leverage long read sequencing 3. Review future applications of long read sequencing f ...
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15:40
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Innovation Stage30 mins
16:10
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Innovation Stage30 minsRecognize the roadblocks to rare disease diagnostics Explore strategies to improve delivery of genomic testing to more families Understand the limitations to care delivery outside of expert centers
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16:40
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Innovation Stage30 minsHow cohort selection impacts observed prevalence of monogenic disorders Why real-world genomic data is critical to overcoming ascertainment bias How large-scale exome/genome datasets can improve disea ...
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17:10
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Innovation Stage30 minsApplying long read sequencing to population-scale studies to identify new structural variants associated with different phenotypes and disease susceptibility. Using advanced computational tools to im ...
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08:20
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Innovation Stage40 mins
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09:00
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Innovation Stage15 minsIn this talk, Carl Zimmer will give us an overview of the odyssey through the living atmosphere and the history of its discovery – including the dark side of aerobiology.
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09:15
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Innovation Stage15 mins
09:30
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Innovation Stage15 minsThis session will cover: Generative AI is rewriting the rules of biology. From proteins to patients, discover how AI foundation models are powering breakthroughs in function prediction, diagnosis, and ...
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09:45
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Innovation Stage15 mins- The Longitude Prize series brings together the brightest minds to solve the world's most challenging innovation problems. Launching at the Festival of Genomics, the Longitude Prize on ALS will bring ...
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10:00
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Innovation Stage30 minsAdvanced molecular diagnostics are transforming the patient care landscape in fields such as dermatology and gastroenterology by addressing critical unmet clinical needs. This discussion will explore ...
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10:30
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Innovation Stage30 minsCan groundbreaking innovations in AI, multi-omics, and biodata reduce the traditional $2.5 billion, 10-year drug development process to a mere 2 years and $2 million? What tools, policies, and collabo ...
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11:00
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Innovation Stage30 mins
11:30
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Innovation Stage30 minsDNA methylations provide an opportunity to investigate the impact of different environmental factors on biological aging. I’ll demonstrate our work focussed on producing an epigenetic aging clock to ...
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12:00
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Innovation Stage30 minsEpigenetic modifications induced by prenatal smoke exposure may have lasting impacts on pulmonary function and susceptibility to respiratory diseases. Through the application of predictive modeling a ...
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12:30
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Innovation Stage30 minsIntroduction of Transcriptional Reporter Elements of Cell State (TRECS) as a novel method to label and distinguish cell states within heterogeneous tumors. • Insights into how EP300/CBP coactivators ...
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13:00
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Innovation Stage5 mins
13:05
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Innovation Stage10 minsMolecular characterization of primary prostate cancer (PCa) is crucial for a better understanding of driver genes and underlying heterogeneity. However, additional approaches such as longitudinal test ...
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13:15
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Innovation Stage10 minsSingle-cell RNA sequencing (scRNA-seq) has improved our ability to characterize tumor heterogeneity, clonal evolution, and therapy resistance. However, detecting expressed driving somatic single-nucle ...
13:25
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Innovation Stage10 minsCentenarians, despite representing a tiny proportion of the global population, hold the key to access longevity. By decoding the genomes in a unique Ashkenazi Jewish (AJ) centenarian cohort, we have i ...
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13:35
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Innovation Stage10 minsNumerous genome-wide association studies (GWAS) have analyzed genetic variants associated with obesity. However, hardly any studies have analyzed the genetics of weight loss. Are the gene variants tha ...
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13:50
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Innovation Stage30 minsI will Present findings from the largest human genomics study of over 90 infectious disease phenotypes using whole genome sequencing (WGS) data from the All of Us Research Program, with replication in ...
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14:20
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Innovation Stage30 minsTraditional medical practice has focused on highly penetrant variants, leaving a gap in the interpretation and classification of "risk alleles" with lower penetrance. This session will introduce a con ...
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14:50
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Innovation Stage30 minsGene therapy vectors and SMRT sequencing Understanding sub-genomic populations in gene therapy products SMRT sequencing to characterize gene therapy products.Speaker(s)
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