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How Can Bacteriophages Treat Antibiotic Resistant Infections
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Rare Variants, Severe Outcomes: Explore how rare, damaging genetic variants identified through whole exome sequencing explain susceptibility to conditions like childhood herpes simplex encephalitis (HSE), severe viral infections, and invasive meningococcal disease (IMD).
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Innate Immunity in Focus: Examine how disruptions in key immune pathways—such as type I/II/III interferons, TLR signaling, and autophagy—compromise pathogen recognition and antiviral/bacterial defense mechanisms.
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Towards Precision Infectious Disease Medicine: Discuss the implications of this work for early diagnosis, targeted therapies, and precision medicine approaches for managing pediatric patients at risk of life-threatening infections.
