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Leveraging single-cell transcriptomics for ALS disease model characterisation and mechanistic insights
- Overview of single-cell technologies and computational approaches for analysing single-cell data
- Insights into the role of C9ORF72 in the pathogenesis of Amyotrophic Lateral Sclerosis (ALS)
- Development of motor neuron–microglia coculture models to study neuroinflammation and C9ORF72-associated ALS pathology
- Single-cell RNA sequencing uncovers altered inflammatory signatures in C9ORF72 cocultures compared to controls
