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Blood-Based Immune Profiling for Early Detection of Brain Cancer
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T-cell recognition of cancer has transformed cancer treatment.
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This recognition has not yet been applied to improve early cancer detection.
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Our work shows that T-cells recognizing a common neo-antigen presented on glioma (a brain tumour) can be leveraged for detection.
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These tumour-specific T-cells can be identified from a peripheral blood sample, enabling tumour detection.
