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Rapid Brain Tumour Classification From Epigenomic Data
- CNS tumors can be classified based on shallow DNA methylation information
- Our probabilistic framework, MethyLYZR, enables rapid classification of malignant transformed tissues from DNA methylation profiles without requiring ad hoc training
- Using ONT sequencing, time-to-diagnosis can be reduced to under 1 hour in an intra-operative setting
- High-quality sequencing data from other platforms also allows for high-throughput, multiplexed classification overnight
