Mapping Molecular Complexity with Spatially-Resolved Proteomics

28 Jan 2026
Spatial Stage
  • Discuss how spatial enables precise mapping of molecular complexity in the brain, revealing region-specific protein expression patterns relevant to neurodegeneration. 

  • Highlight comparative neuropathology across human and mouse models to understand mechanisms driving regional vulnerability in Parkinson’s disease and to validate new MRI-based biomarkers. 

  • Present how integrating spatial with other omics with newly generated Parkinson’s models supports deeper insight into disease mechanisms and strengthens translational pathways toward improved diagnostics and therapies. 

Speakers
Olaf Ansorge
Olaf Ansorge, Lead Clinical Neuropathologist, and Director of the Thomas Willis Oxford Brain Collection - University of Oxford