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Utilising Liquid Biopsy for Diagnosis and Surveillance of MRD in Head and Neck Cancer
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Head and neck cancer is the eighth commonest cancer in the UK
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Over half are caused by infection with human papillomavirus (HPV)
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Analysis of plasma cell-free DNA - or liquid biopsy - can be used as a minimally invasive test for diagnosis and surveillance in head and neck cancer
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We show that liquid biopsy analysis of plasma HPV is highly concordant with traditional tissue-based testing for HPV at diagnosis of head and neck cancer and can predict and diagnose recurrence before clinical presentation or diagnosis by imaging
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Liquid biopsy is a valuable addition to traditional means of managing head and neck cancer
