Mirjana Efremova, Barts Cancer Institute
Mirjana Efremova
Group Leader
Barts Cancer Institute

Mirjana did her PhD at the Medical University of Innsbruck, Austria, where she investigated the process of clonal evolution of cancer under immunosurveillance and how the immune system shapes tumour progression. For her postdoctoral research, she joined the Teichmann Lab (Wellcome Sanger Institute) where she co-led the development of the first human atlas of the maternal-fetal interface in early pregnancy using single cell transcriptomics. She also developed a cell-cell communication statistical framework CellPhoneDB (www.cellphonedb.org) for predicting enriched receptor-ligand pairs between the different cell types and inference of cellular communication networks. This framework allowed her to dissect the complex interplay between stromal and immune cells in the dynamic tumour microenvironment in melanoma. In May 2020 she started her own lab at Barts Cancer Institute, Queen Mary University of London (UK) within the Centre for Cancer Genomics and Computational Biology. Her lab’s research interests are focused on investigating the cellular and molecular mechanisms that promote cancer cell plasticity and adaptation of tumour cells in metastatic niches and under therapeutic pressure.