Originally, my PhD training was in mathematics and population genetics. Through a series of academic research positions [Vancouver, Rothamsted, Edinburgh, Leeds, Lausanne, QMUL] I developed research interests in statistical genetics methodology and in human genetic data analysis, with a focus on cardiovascular and metabolic disease. In 2012 I joined GSK, initially working in oncology pharmacogenomics. Through leading teams working on GWAS database and analysis methods in particular for UK Biobank and 23andMe collaborations, I now lead the Genomic Technologies team of 40 scientists working on methods for integrating genetic, genomic, and functional genomic data to inform drug discovery and in clinical translation.