Professor Deborah Tweddle is an Honorary Consultant in Paediatric and Adolescent Oncology at the Great North Children’s Hospital (GNCH) and Professor of Paediatric Oncology in the Newcastle University Centre for Cancer within the Translational & Clinical Research Institute at Newcastle University. Professor Tweddle has a specific interest in childhood neuroblastoma research – biological, translational and clinical – which she has specialised in for over 20 years. As a clinical academic in paediatric oncology, Professor Tweddle spends most of her time at Newcastle University supervising her research team or undertaking duties related to the VIVO biobank, a national biobank of samples from children and young people with cancer and leukaemia for which she is the Scientific Director. The remainder of her time is spent looking after patients with neuroblastoma at the GNCH and co-directing the National Neuroblastoma Molecular Genetics Reference centre service with her NHS cytogenetics colleagues. Professor Tweddle has particular research interests in the genetics of neuroblastoma liquid biopsies, pre-clinical drug development, new neuroblastoma models and the epidemiology of relapsed neuroblastoma.