Professor Tatton Brown qualified with a BMBCh from the University of Oxford in 1996, before earning an MD in 2006. She undertook her professional training at Great Ormond Street and St George's Hospitals. As well as her NHS clinical practice, Professor Tatton Brown runs a research study to investigate the genetic causes and clinical presentations of conditions associated with a learning disability and increased growth. In addition, she is committed to educating and training the healthcare workforce in genomics.