Professor Zhengming Chen is an elected Member of Academia Europaea and inaugural Richard Peto Chair Professor in Epidemiology at the Nuffield Department of Population Health, University of Oxford. He qualified in medicine at Shanghai Medical University in 1983, followed by further postgraduate training in public Health in China and DPhil in Epidemiology at University of Oxford in 1991. His main research concerns causes, prevention and treatment of major chronic diseases of adults (e.g. IHD, stroke, diabetes, cancer) and development of precision health, using big data and multi-omics approaches. Over the last three decades, he has led several large randomised trials of stroke, heart diseases and certain cancers involving in total >100,000 patients, leading to major changes of international guidelines and clinical practice. In 2003, he initiated, designed and established in collaboration with research institutes in China, and has led ever since as UK PI, the China Kadoorie Biobank of >512,000 adults (www.ckbiobank.org), which will continue for the next 15-20 years. In Oxford he leads a large and expanding multi-disciplinary research team. He has published >640 papers (h-Index: >120; total citations>100,000), with expertise in a range of research areas including epidemiology, proteomics, genomic medicine and clinical trials.