Rob Ewing is Professor in Cancer Systems Biology at the University of Southampton, UK. He received his DPhil from the University of Oxford in molecular genetics, worked as a postdoc in the CNRS and at Carnegie Institute/Stanford University, where he developed computational techniques for the analysis of large-scale 'omics data. As a bioinformatics scientist in industry (Incyte Genomics, Palo Alto; MDS Proteomics, Toronto), he developed interests in using massive genomic and proteomic data-sets to understand human protein interaction networks. His laboratory currently focuses on applying proteomic and computational methods to map protein-protein interaction networks that drive human disease and development. Specific and current interests include computational approaches to network-based integration of 'omics data with applications in developing an oncolytic virotherapy against brain tumours.