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Alex Frankell
Group Leader,
University of Cambridge
Alex Frankell's Somatic Evolution Monitoring (SEM) lab focuses on methods to detect and track evolution occurring in premalignant and neoplastic tissues using longitudinal, minimally-invasive samples, for example circulating tumour DNA in blood. The lab develops and applies novel molecular and computational methods to these samples, working closely with several clinical collaborators, with a focus on lung and oesophageal cancer.
The lab aims to leverage these technologies to understand the selection pressures driving tumour initiation and evolution, as well as to form the basis of novel diagnostics for pre-invasive risk stratification, early cancer detection and drug response prediction.
Sessions
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Longitudinal Tracking of Lung Cancer Clonal Dynamics using Circulating Tumour DNA28-Jan-2027Cancer Diagnostics Stage